Immune Thrombocytopenia (ITP): Current Limitations in Patient Management
نویسندگان
چکیده
منابع مشابه
Immune thrombocytopenia (ITP): an historical perspective.
See the related ASH 50th Anniversary Review articles under the PLATELETS AND MEGAKARYOCYTOPOIESIS section of the publication ASH 50th Anniversary Reviews: A Salute to the American Society of Hematology. In 1735, two young girls presented to the German physician Paul Gottlieb Werlhof with symptoms of epistaxis and purpura. One young patient had a spontaneous remission, while the second suffered ...
متن کاملCurrent Management of Primary Immune Thrombocytopenia
Primary immune thrombocytopenia is an autoimmune disorder of unknown cause affecting both children and adults. The low peripheral blood platelet count is caused by premature platelet destruction by self-reacting antibodies in addition to an impairment of platelet production. The disease is heterogeneous in its pathophysiology, clinical features and responses to treatment. To date, most of the t...
متن کاملPathogenesis and Therapeutic Mechanisms in Immune Thrombocytopenia (ITP)
Immune thrombocytopenia (ITP) is a complex autoimmune disease characterized by low platelet counts. The pathogenesis of ITP remains unclear although both antibody-mediated and/or T cell-mediated platelet destruction are key processes. In addition, impairment of T cells, cytokine imbalances, and the contribution of the bone marrow niche have now been recognized to be important. Treatment str...
متن کاملImmune Thrombocytopenia (ITP) Secondary to Subclinical Hashimoto’s Thyroiditis
Immune thrombocytopenia (ITP) is the most common cause of isolated thrombocytopenia in healthy people. ITP may rarely coexist with autoimmune thyroid disorders, which may indicate more complex defect in immune system. Primary ITP usually responds well to steroids and intravenous immunoglobulins. However, ITP may be difficult to treat when associated with thyroid autoimmune disorders. In such ca...
متن کاملImmune thrombocytopenia (ITP): a rare association of lymph node tuberculosis.
Although various haematologic abnormalities are known to occur with tuberculosis, association of immune thrombocytopenia with tuberculosis is uncommon. We report a case of retroperitoneal lymph node tuberculosis who presented with ITP. A 76 year old female was admitted to our hospital with oral mucosal bleed and petechial lesions over extremities and abdomen. A diagnosis of immune thrombocytope...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Medicina
سال: 2020
ISSN: 1648-9144
DOI: 10.3390/medicina56120667